Spirocyclopropane Carboxylic Acids Derived from 1-Tetralone and 4-Chromanone and their Conversion to the Corresponding Pyridazinones

Giorgio Cignarella; Daniela Barlocco; Guendalina Rossi; Elisabetta Rossi

doi:10.1055/s-1990-26821

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Synthesis 1990; 1990(2): 160-162
DOI: 10.1055/s-1990-26821

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Spirocyclopropane Carboxylic Acids Derived from 1-Tetralone and 4-Chromanone and their Conversion to the Corresponding Pyridazinones

Giorgio Cignarella^* , Daniela Barlocco, Guendalina Rossi, Elisabetta Rossi

^*Istituto di Chimica Farmaceutica e Tossicologica, Università di Milano, Viale Abruzzi, 42,I-20131 Milano, Italy

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Publication Date:
17 September 2002 (online)

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The title compounds were synthesized starting from 1-tetralone and 4-chromanone. Structure and configurational identification of the two isomers were assigned on the basis of ¹H-NMR data.

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