Download PDF
Synthesis 1990; 1990(4): 313-314
DOI: 10.1055/s-1990-26861
paper
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.

Regioselective Reductive Alkylation of 3,4,5-Trimethoxybenzaldehyde Dimethylacetal: A New Synthesis of 4-Alkyl-3,5-dimethoxybenzaldehydes and 2,5-Dialkyl-1,3-dimethoxybenzenes

Ugo Azzena* , Sergio Cossu, Teresa Denurra, Giovanni Melloni, Anna Maria Piroddi
  • *Dipartimento di Chimica, Universita' di Sassari, Via Vienna 2, I-07100 Sassari, Italy
Further Information

Publication History

Publication Date:
17 September 2002 (online)

 PDF Download  Permissions and Reprints All articles of this category
Preview

The regioselective replacement of the 4-methoxy group of 3,4,5-trimethoxybenzaldehyde dimethylacetal by an alkyl group under reductive electron-transfer conditions has been employed as a key step in a new synthesis of 2,5-dialkyl-1,3-dimethoxybenzenes via the corresponding 4-alkyl-3,5-dimethoxybenzaldehydes.