PDF herunterladen
Synthesis 1990; 1990(6): 502-504
DOI: 10.1055/s-1990-26920
paper
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.

The Addition of Lithium Salts of O-Alkyloximes to Aldehydes: Synthesis of ß-Keto O-Alkyloximes

Shimon Shatzmiller* , Eliezer Bahar, Sorin Bercovici, Alexander Cohen, Gerhard Verdoorn
  • *The Beverly and Raymond Sackler Faculty of Exact Sciences, School of Chemistry, Tel-Aviv University, Ramat-Aviv, Tel-Aviv 69978, Israel
Weitere Informationen

Publikationsverlauf

Publikationsdatum:
17. September 2002 (online)

  als PDF herunterladen  Lizenzen und Reprints Alle Artikel dieser Rubrik

Addition of lithium salts of oxime O-ethers to aldehydes affords the thermodynamically unfavored ß-hydroxy (Z)-O-alkyloximes. Oxidation of the hydroxy function with chromium trioxide/pyridine complex gives the ß-keto O-alkyloximes. Facile alkylation of the 1,3-dicarbonyl analogs is possible via their sodium or lithium salts.

      >