Synthesis 1990; 1990(6): 511-514
DOI: 10.1055/s-1990-26923
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Flavonoids, 42.1 Anomalous Intramolecular Conjugate Addition: Synthesis of 2-Amino-2-benzyl-3(2H)-benzofuranone and Related Compounds

Erzsébet Patonay-Péli* , György Litkei, Tamás Patonay
  • *Department of Organic Chemistry, Kossuth Lajos University H-4010 Debrecen, POB 20, Hungary
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Publikationsverlauf

Publikationsdatum:
17. September 2002 (online)

An easy and convenient preparation of 2-amino-2-benzyl-3(2H)-benzofuranone and related compounds is described. The method utilizes the anomalous intramolecular conjugate addition of intermediate 2-amino-1-(2-hydroxyphenyl)-3-phenyl-2-propen-1-ones. 2-Benzyl-2-triphenylphosphoranylideneamino-3(2H)-benzofuranones by an analogous method are extremely unreactive and have limited synthetic applicability.

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