Download PDF
Synthesis 1991; 1991(9): 743-744
DOI: 10.1055/s-1991-26563
paper
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.

A Novel Dieckmann-Type Cyclization, the Final Step of the Synthesis of a Carbacephem Derivative

Gebhard Neyer* , Ivar Ugi
  • *Institut für Organische Chemie der Technischen Universität München, D-8046 Garching, Germany
Further Information

Publication History

Publication Date:
29 April 2002 (online)

  PDF Download  Permissions and Reprints All articles of this category

The treatment of the triacylamine, methyl 4-(dibenzoylaminocarbonylethyl)-2-oxoazetidine-1-acetate (2), with sodium bis(trimethylsilyl)amide leads to an unprecedented Dieckmann-type ring closure to form the anion of the carbacephem derivative, methyl 3-hydroxy-1-carbacephem-4-carboxylate, (3).

      >