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Synthesis 1991; 1991(9): 763-764
DOI: 10.1055/s-1991-26569
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An Improved Procedure for the Preparation of Alkyl N-(4-Aryl-2-thiazolyl)oxamates

Patrick Lesimple* , Dennis C. H. Bigg
  • *Centre de Recherche Pierre Fabre, 17 avenue Jean-Moulin, F-81106 Castres, France
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Publication Date:
29 April 2002 (online)

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2-Amino-4-arylthiazoles react cleanly with dialkyl oxalates in the presence of sodium alkoxides at room temperature to afford alkyl N-(4-aryl-2-thiazolyl)oxamates in high yield.

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