Download PDF
Synlett 1992; 1992(6): 510-512
DOI: 10.1055/s-1992-21397
letter
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.

Opening of Epoxides to Olefins or Halohydrins with Vanadium (II)-Tetrahydrofuran or Vanadium(III)-Tetrahydrofuran Complexes

Tsutomu Inokuchi* , Hiroyuki Kawafuchi, Sigeru Torii
  • *Department of Applied Chemistry, Faculty of Engineering, Okayama University, Okayama 700, Japan
Further Information

Publication History

Publication Date:
08 March 2002 (online)

  PDF Download  Permissions and Reprints All articles of this category

A variety of epoxides were deoxygenated to give the corresponding alkenes through the use of a [V2Cl3(THF)6]2[Zn2Cl6] complex prepared from VCl3(THF)3 and zinc. The reaction proceeds with a partial inversion of the configuration of the acyclic cis epoxide. Treatment of the epoxides with the vanadium(III) reagent, VCl3(THF)3, afforded the corresponding chlorohydrins in good yields.