Download PDF
Synlett 1993; 1993(2): 139-140
DOI: 10.1055/s-1993-22379
letter
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.

Chiral Template Approach to 1,2-Disubstituted Carbacephem Antibiotics: Highly Chemoselective Reactions of Bicyclic Lactam Intermediates Bearing Multi-Carbonyl Functions with Nucleophiles

Seiki Saito* , Teruhiko Ishikawa, Toshio Moriwake
  • *Department of Applied Chemistry, Faculty of Engineering, Okayama University, 3-1-1 Tsushima-naka, Okayama 700, Japan
Further Information

Publication History

Publication Date:
19 March 2002 (online)

  PDF Download  Permissions and Reprints All articles of this category

Diazabicyclio[4.2.0]-system consisted of N-(p-methoxyphenyl)-β-lactam and N′-Boc-δ-lactam subunits undergoes highly chemoselective reaction with various carbon nucleophiles at the carbonyl group of the δ-lactam-ring to give substituted β-lactam derivatives as precursors required for 1,2-disubstituted carbacephem antibiotics.

      >