Download PDF
Synlett 1993; 1993(10): 774-776
DOI: 10.1055/s-1993-22605
letter
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.

The Horner-Wadsworth-Emmons Reaction in Natural Products Synthesis: Expedient Construction of Complex (E)-Enones Using Barium Hydroxide

Ian Paterson* , Kap-Sun Yeung, Jeff B. Smaill
  • *University Chemical Laboratory, Lensfield Road, Cambridge CB2 1EW, England
Further Information

Publication History

Publication Date:
19 March 2002 (online)

 PDF Download  Permissions and Reprints All articles of this category

The barium hydroxide promoted Horner-Wadsworth-Emmons reaction is a mild and efficient method for the coupling of ß-ketophosphonates with structurally complex, base-sensitive aldehydes in equimolar quantities to give (E)-enones.