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Synthesis 1993; 1993(12): 1227-1229
DOI: 10.1055/s-1993-26030
short paper
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Simple Preparation of Polyhydro-6-aryl(heteroaryl)cycloalka[b][1,5]naphthyridines

Axel Couture* , Eric Deniau, Pierre Grandclaudon, Cristian Simion
  • *Laboratoire de Chimie Organique Physique, URA CNRS No 351, Université des Sciences et Technologies de Lille I, F-59655 Villeneuve d'Ascq Cedex, France
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Publication Date:
29 April 2002 (online)

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A variety of polyhydro-6-aryl- and heteroarylcycloalka[b][1,5] naphthyridines have been efficiently prepared by thermally induced ring contraction of pyrido[2,3-b][1,5]thiazepines obtained by reacting lithiated 2-chloro-N-cycloalkylidene-3-pyridinimines with suitable O-ethyl thiocarboxylates.

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