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Synlett 1994; 1994(3): 219-220
DOI: 10.1055/s-1994-22802
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A New Method for the Deprotection of Benzyl Esters

Michael S. Anson* , John G. Montana
  • *Process Research Department, Glaxo Research and Development Limited, Park Road, Ware, Hertfordshire SG12 ODP, UK.
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Publication Date:
22 March 2002 (online)

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N-Bromosuccinimide can be used to selectively convert benzyl esters into carboxylic acids under neutral conditions. This method provides an alternative complementary method to hydrogenolysis.

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