Stereoselective Heteroaromatic Homolytic Substitution with Carbon Radicals Derived from Oppolzer's Camphorsultam
22 March 2002 (online)
The first example of stereoselective homolytic aromatic substitution of pentatomic heteroaromatics (N-methylpyrrole, furan and thiophene) with a chiral carbon radical, derived from Oppolzer's camphor sultam, is described. The stereoselectivity is extremely good >98% d.e.) with pyrrole and furan, and good (82% d.e.) with thiophene.