Download PDF
Synthesis 1995; 1995(1): 69-72
DOI: 10.1055/s-1995-3855
paper
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.

Preparation of Secondary Alkyl and Benzylic Zinc Bromides Using Activated Zinc Metal Deposited on Titanium Oxide

Heinz Stadtmüller, Björn Greve, Klaus Lennick, Abdellatif Chair, Paul Knochel*
  • *Fachbereich Chemie der Philipps-Universität Marburg, D-35032 Marburg, Germany
Further Information

Publication History

Publication Date:
31 December 2000 (online)

  PDF Download  Permissions and Reprints All articles of this category

Sodium dispersed on titanium oxide readily reduces zinc chloride leading to a highly active zinc powder which inserts into secondary alkyl and benzylic bromides under mild conditions, producing the corresponding zinc reagents in high yields. Compared to zinc dust, this activated zinc allows the preparation of secondary benzylic zinc bromides with significantly less Wurtz-coupling products.

sodium - titanium oxide - activated zinc - alkyl bromides

      >