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Synlett 1997; 1997(11): 1277-1278
DOI: 10.1055/s-1997-1028
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α-Halogenation of Ester Enolates Containing an N-Unprotected Pyrrole Nucleus

Stefan E. Boiadjiev1 , David A. Lightner2
  • 1Department of Chemistry, University of Nevada, Reno, Nevada 89557, USA, Fax: 702-784-6804; email: lightner@chem.unr.edu
  • 2Department of Chemistry, University of Nevada, Reno, Nevada 89557, USA, Fax: 702-784-6804
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Publication History

Publication Date:
31 December 2000 (online)

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The reaction of ester enolates derived from unprotected (1H-pyrrol-3-yl)propionates with CCl4, CBr4 and I2 cleanly provides α-halogenated esters.

halogenation - α-ester enolates - bilirubin

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