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Synlett 1999; 1999(S1): 984-986
DOI: 10.1055/s-1999-3109
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Addition of 2-Lithiothiazoles to ROPHy/SOPHy Aldoximes: Asymmetric Synthesis of 1-(2-Thiazolyl)ethylamines

Christopher J. Moody* , James C. A. Hunt
  • *School of Chemistry, University of Exeter, Stocker Road, Exeter, EX4 4QD, UK; Fax +44(13 92)26 34 34; E-mail: c.j.moody@exeter.ac.uk
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Publikationsdatum:
31. Dezember 1999 (online)

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A new asymmetric synthesis of 1-(2-thiazolyl)ethylamines is described in which the key step is the diastereoselective addition of 2-lithiothiazoles to O-(1-phenylbutyl) aldoximes.

oxime ether - hydroxylamine - thiazole