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Synthesis 1999; 1999(2): 225-227
DOI: 10.1055/s-1999-3376
DOI: 10.1055/s-1999-3376
short paper
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Synthesis of Phenylthiomethyl Compounds from Trichloromethyl Derivatives
Further Information
Publication History
Publication Date:
31 December 1999 (online)
A new method for the conversion of trichloromethyl compounds into the corresponding phenylthiomethyl derivatives by reaction with sodium thiophenolate in the presence of thiophenol is described. This transformation proceeds at room temperature in high yield and has been applied to a variety of trichloromethyl compounds.
trichloromethyl compounds - thiophenol - sodium thiophenolate - phenylthiomethyl derivatives - nucleophilic substitution