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Synlett 2001; 2001(5): 0670-0672
DOI: 10.1055/s-2001-13377
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P(MeNCH2CH2)3N: An Efficient Catalyst for the Synthesis of Substituted Ethyl Benzofuran-2-Carboxylates

Bosco A. D'Sa* , Philip Kisanga, John G. Verkade
  • *Department of Chemistry, Iowa State University, Ames, Iowa 50011; Fax 515-294-0105; E-mail: jverkade@iastate.edu
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Publication Date:
31 December 2001 (online)

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A superior method for the synthesis of substituted ethyl benzofuran-2-carboxylates in 80-99% yields from substituted 2-formylphenoxy ethylcarboxylates using 0.4 equiv of commercially available P(MeNCH2CH2)3N at 70 °C for 3 hours is described.

benzofurans - bicyclic compounds - catalysis - cyclizations - heterocyclics

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