Synthesis 2001(14): 2165-2169
DOI: 10.1055/s-2001-18068
PAPER
© Georg Thieme Verlag Stuttgart · New York

InCl3-Catalysed Conjugate Addition of Indoles with Electron-Deficient Olefins [1]

J. S. Yadav*, Sunny Abraham, B. V. S. Reddy, G. Sabitha
Division of Organic Chemistry, Indian Institute of Chemical Technology, Hyderabad 500 007, India
Fax: +91(40)7170512; e-Mail: [email protected];
Further Information

Publication History

Received 18 April 2001
Publication Date:
09 August 2004 (online)

Abstract

Indole and 2-methylindole undergo conjugate addition with electron-deficient olefins in the presence of a catalytic amount of InCl3 at ambient temperature to afford the corresponding Michael adducts in excellent yields with high selectivity.

1

IICT communication No. 4745.

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1

IICT communication No. 4745.