An Efficient Synthesis of Polysubstituted 3-Halo-2(1H)-Pyridinones

Claude Agami; Luc Dechoux; Séverine Hebbe; Julien Moulinas

doi:10.1055/s-2002-19310

PAPER

An Efficient Synthesis of Polysubstituted 3-Halo-2(1H)-Pyridinones

Claude Agami, Luc Dechoux*, Séverine Hebbe, Julien Moulinas
Laboratoire de Synthèse Asymétrique associé au CNRS, Université Pierre et Marie Curie, 4 Place Jussieu, 75005 Paris, France
Fax: +(33)0144272620; e-Mail: dechoux@ccr.jussieu.fr;

Abstract

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Abstract

A series of 3-halo-2(1H)-pyridinones 4 have been synthesized by treatment of δ-dienaminoesters 1 with N-halosuccinimide in basic medium. The chemoselectivity of the reaction is discussed.

Key words

pyridinones - pyrroles - δ-dienaminoesters

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References

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