Planta Med 2002; 68(5): 430-434
DOI: 10.1055/s-2002-32078
Original Paper
Natural Product Chemistry
© Georg Thieme Verlag Stuttgart · New York

New Oxypregnane Glycosides from
Caralluma penicillata

Essam Abdel-Sattar1 , Meselhy R. Meselhy1 , Mohammed Abdul-Aziz Al-Yahya2
  • 1Department of Pharmacognosy, College of Pharmacy, Cairo University, Cairo, Egypt
  • 2Department of Pharmacognosy, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia
Further Information

Publication History

July 24, 2001

November 9, 2001

Publication Date:
07 June 2002 (online)

Abstract

The ether fraction of the defatted ethanol extract of the aerial parts of Caralluma penicillata (defl) M. E. Br. (Asclepiadaceae) yielded four new oxypregnane glycosides, penicillosides D-G. The structures of the isolated compounds were established by different spectroscopic methods.

References

  • 1 Deepak D, Khare A, Khare M P. Plant Pregnanes.  Phytochemistry. 1989;  28 3255-63
  • 2 Deepak D, Srivastav S, Khare A. Pregnane glycosides.  Fortschritte der Chemie Organischer Naturstoffe. 1997;  71 169-325
  • 3 Al-Yahya M A, Abdel-Sattar E, Guittet E. Pregnane glycosides from Caralluma russeliana .  J. Nat. Prod.. 2000;  63 1451-3
  • 4 Abdel-Sattar E, Al-Yahya M A, Nakamura N, Hattori M. Penicillosides A-C, C-15 oxypregnane glycosides from Caralluma penicillata .  Phytochemistry. 2001;  57 1213-7
  • 5 Yoshimura S I, Narita H, Hayashi K, Mitsuhashi H. Studies on the constituents of Asclepiadaceae plants, LVI: Isolation of new antitumor-active glycosides from Dregea volubilis (L) Benth.  Chem. Pharm. Bull.. 1983;  31 3971-83
  • 6 Itokawa H, Xu J, Takeya K, Watanabe K, Shoji J. Studies on chemical constituents of antitumour fractions from Periploca sepium, II: Structures of new pregnane glycosides, periplocosides A, B and C.  Chem. Pharm. Bull.. 1988;  36 982-7
  • 7 El Sayed K A, Halim A F, Zaghloul A M, McChesney J D, Stone M P, Voehler M, Hayashi K. Pregnane glycosides from Stapelia variegata .  Phytochemistry. 1995;  39 395-403
  • 8 Rasoanaivo P, Kaneda N, Kinghorn A D, Farnsworth N R. Folotsoside A, a new pregnane glycoside from Folotsia sarcostemmoides .  J. Nat. Prod.. 1991;  54 1672-6
  • 9 Halim A F, Khalil A T. Pregnane glycosides from Caralluma retrospiciens .  Phytochemistry. 1996;  42 1135-9
  • 10 Chen J J, Zhang Z X, Zhou J, Li B T. New pregnane glycosides from Sinomarsdenia incisa .  J. Nat. Prod.. 1999;  62 829-32
  • 11 Piacente S, Belisario M A, Castillo H D, Pizza C, Feo V D. Croton ruizianus: Platelet proaggregating activity of two new pregnane glycosides.  J. Nat. Prod.. 1998;  61 318-22
  • 12 Abe F, Yamauchi T. Pregnane glycosides from the roots of Asclepias tuberosa .  Chem. Pharm. Bull.. 2000;  48 1017-22
  • 13 Terada S, Hayashi K, Mitsuhashi H. On the structure of stephanthraniline C.  Tetrahedron Lett.. 1978;  23 1995-8
  • 14 Warashina T, Noro T. Steroidal glycosides from the aerial part of Asclepias incarnata .  Phytochemistry. 2000;  53 485-98
  • 15 Tanaka T, Tsukamoto S, Hayashi K. Pregnane glycosides from Boucerosia aucheriana .  Phytochemistry. 1990;  29 229-37
  • 16 Yuan J L, Lu Z Z, Chen G X, Ding W P, Zhou B N, Erdelmeier C AJ, Hamburger  M O, Fong H HS, Cordell G A. The pregnane glycoside marsdekoiside A from Marsdenia Koi .  Phytochemistry. 1992;  31 1058-60
  • 17 Agrawal P K. NMR spectroscopy in the structural elucidation of oligosaccharides and glycosides.  Phytochemistry. 1992;  31 3307-30
  • 18 Yoshikawa K, Okada N, Kan Y, Arihara S. Steroidal glycosides from the fresh stem of Stephanotis lutchuensis var. japonica (Asclepiadaceae). Chemical structures of stephanosides K-Q.  Chem. Pharm. Bull.. 1996;  44 2243-8

Dr. Essam Abdel-Sattar

Department of Pharmacognosy, College of Pharmacy

Cairo University, Kasr El-Aini street

Cairo 11562, Egypt

Email: abdel-sattar@excite.com

Fax: (+202)-3635140

Phone: (+202)-3624917

    >