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Synthesis 2002(14): 2091-2095
DOI: 10.1055/s-2002-34378
PAPER
© Georg Thieme Verlag Stuttgart · New York

Synthesis and Conformational Analysis of a Novel Ansadipeptide

Johann Mulzer*, Oliver Langer
Institut für Organische Chemie, Universität Wien, Währinger Strasse 38, 1090 Wien, Austria
Fax: +43(1)427752189; e-Mail: johann.mulzer@univie.ac.at;
Further Information

Publication History

Received 13 June 2002
Publication Date:
26 September 2002 (online)

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Abstract

A novel ansapeptide 6 was synthesized from tyrosine (5) and Bic 3b as the amino acid components and oxalic acid as the connecting link. The conformational properties of 6 were calculated by molecular mechanics.

Key words

ansa compounds - peptidomimetics - β-amino acids - conformation analysis - molecular mechanics

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