Ring Opening of Epoxides and Aziridines with Sodium Azide using Oxone^®
in Aqueous Acetonitrile: A Highly Regioselective Azidolysis Reaction [1]

Abstract

A wide variety of epoxides and aziridines were converted to the corresponding β-azido alcohols and β-azido amines with sodium azide using Oxone^® in aqueous acetonitrile. The reactions were highly regioselective and efficient with excellent yields at room temperature under mild reaction conditions.

Keywords

Oxone^® - epoxides - aziridines - azides - regioselectivity

1

IICT communication No. 03/02/02.

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IICT communication No. 03/02/02.

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Sabitha, G.; Satheesh Babu, R.; Shashikumar, M; Yadav, J. S. New. J. Chem., 2002, in press.