Composition and Antimicrobial Activity of the Essential Oil of Achillea multifida

K. HüsnüCan Başer; Betül Demirci; Fatih Demirci; Serkan Koçak; Çağrı Akıncı; Hulusi Malyer; Gürcan Güleryüz

doi:10.1055/s-2002-34923

Planta Med 2002; 68(10): 941-943
DOI: 10.1055/s-2002-34923

Letter

Composition and Antimicrobial Activity of the Essential Oil of Achillea multifida

K. Hüsnü Can Başer¹ , Betül Demirci¹ , Fatih Demirci¹ , Serkan Koçak² , Çağrı Akıncı² , Hulusi Malyer³ , Gürcan Güleryüz³

¹Medicinal and Aromatic Plant and Drug Research Centre (TBAM), Anadolu University, Eskişehir, Turkey
²Fatih Science High School, Eskişehir, Turkey
³Department of Biology, Faculty of Science and Letters, Uludag˘ University, Bursa, Turkey

Abstract

The composition of the water-distilled essential oil of Achillea multifida (DC.) Boiss. (Compositae) was analysed by GC and GC/MS. Fifty-eight compounds were identified representing 93.9 % of the total oil. α-Thujone (60.9 %), β-thujone (9.1 %), sabinene (4.1 %) and camphor (3.7 %) were characterised as the main constituents. The essential oil was tested for its antimicrobial activity using a micro-dilution assay resulting in the inhibition (MIC: 62.5 - 250 μg/ml) of human pathogenic bacteria and yeast.

Full Text

References

1 Davis P H. Flora of Turkey and the East Aegean Islands. Vol. 5 University Press Edinburgh; 1982: p. 229
2 Güner A, Özhatay N, Ekim T, Başer K HC. Flora of Turkey and The East Aegean Islands. Vol. 11 University Press Edinburgh; 2000
3 Baytop T. Türkiye’de Bitkiler ile Tedavi Geçmişten Bugüne (Therapy with Medicinal Plants in Turkey-Past and Present). 2nd Ed Nobel Tıp Basımevi Istanbul, Turkey; 1999: p. 177
4 Güleryüz G. Achillea multifida (DC.) Boiss. (Compositae). The Karaca Arboretum Magazine. 1999; 5 43-4
5 Chatzopoulou P, Katsiotis S T, Baerheim-Svendsen A. An ascaridole containing essential oil of the Achillea millefolium L. complex growing wild in northern Greece. J Essent Oil Res. 1992; 4 457-9
6 Hanlidou E, Kokkalou E, Kokkini S. Volatile constituents of Achillea grandifolia . Planta Med. 1992; 58 105-7
7 Küsmenoglu S, Başer K HC, Özek T, Harmandar M, Gökalp Z. Constituents of the Essential Oil of Achillea biebersteinii Afan. J Essent Oil Res. 1995; 7 527-8
8 Başer K HC, Demirci B, Kaiser R, Duman H. Composition of the essential oil of Achillea phrygia Boiss.et Ball. J Essent Oil Res. 2000; 12 327-9
9 Başer K HC, Demirci B, Duman H, Aytaç Z, Adıgüzel N. Composition of the essential oil of Achillea goniocephala Boiss. et Bal. from Turkey. J Essent Oil Res. 2001; 13 219-20
10 Başer K HC, Demirci B, Duman H. Composition of the essential oils of two endemic species from Turkey: Achillea lycaonica and A. ketenoglui . Chem Nat Comp. 2001; 37 245-52
11 Aljancic I, Vajs V, Menkovic N, Karadzic I, Juranic N, Milosavljevic S. et al . Flavones and sesquiterpene lactones from Achillea atrata subsp, multifida: antimicrobial activity. J Nat Prod. 1999 ; 62 909-11
12 Koneman E W, Allen S D, Janda W M, Schreckenberger P C, Winn W C. Color Atlas and Textbook of Diagnostic Microbiology. Lippincott-Raven Pub Philadelphia, PA; 1997: p. 785-6
13 Hammer K A, Carson J F, Riley T V. Antimicrobial activity of essential oils and other plant extracts. J Appl Microbiol. 1999; 86 985-90
14 Dorman H JD, Deans S G. Antimicrobial agents from plants: antibacterial activity of plant volatile oils. J Appl Microbiol. 2000; 88 308-16
15 Barel S, Segal R, Yashphe J. The antimicrobial activity of the essential oil from Achillea fragrantissima . J Ethnopharmacol. 1991; 33 187-91
16 Fiori A CG, Schwan-Estrada K RF, Stangarlin J R, Vida J B, Scapim C A, Cruz M ES. Antifungal activity of leaf extracts and essential oils of some medicinal plants against Didymella bryoniae . J Phytopathol. 2000; 148 483-7

Prof. Dr. K. Hüsnü Can Başer

Medicinal and Aromatic Plant and Drug Research Centre (TBAM)

Anadolu University, 26470-Eskişehir, Turkey.

Email: khcbaser@anadolu.edu.tr or khcbaser@yahoo.co.uk