One-Pot Synthesis of New Chiral Sulfides and Selenides Containing Oxazolidines­: Catalyst in the Enantioselective Addition of Diethylzinc to Benzaldehyde­

Abstract

A new easily accessible class of chiral sulfides 1 and selenides 2 containing oxazolidine was prepared from amino acids. They were used as chiral ligands in the catalytic asymmetric addition of diethylzinc to benzaldehyde to give the corresponding secondary alcohols in up to 80% ee with an R-configuration.

Key words

sulfur - selenium - stereoselective synthesis - asymmetric catalysis - zinc

References

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