Abstract
δ-Hydroxy-α,β-unsaturated aldehydes undergo a tandem Michael and intramolecular Friedel-Crafts
type cyclization with arylamines in the presence of 10 mol% InCl3 under mild conditions to afford a novel class of optically active tetrahydroquinolines
in good yields with high stereoselectivity. The stereochemistry of the products was
determined using various NMR experiments.
Key words
arylamines - α,β-unsaturated aldehydes - benzo-fused heterobicycles
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