Planta Med 2005; 71(6): 575-577
DOI: 10.1055/s-2005-864164
Letter
© Georg Thieme Verlag KG Stuttgart · New York

Chemical Composition and Antimicrobial Activity of the Essential Oil of Artemisia lavandulaefolia

Jeong-Dan Cha1 , Mi-Ran Jeong2 , Hwa-Jung Choi3 , Seung-Il Jeong4 , Sang-Eun Moon1 , Soon-Il Yun5 , Young-Hoi Kim6 , Bong-Seop Kil7 , Yo-Han Song1
  • 1Institute of Oral Bioscience and Department of Oral Microbiology, School of Dentistry, Chonbuk National University, Jeonju, South Korea
  • 2Department of Herbal Resources, Professional Graduate School of Oriental Medicine, Wonkwang University, Iksan, South Korea
  • 3Institute of Oral Bioscience and Department of Pharmacology, School of Dentistry, Chonbuk National University, Jeonju, South Korea
  • 4Department of Bio and Medicinal Chemistry, College of Natural Science, Mokwon University, Taejon, South Korea
  • 5Food Science and Technology Major, Division of Biotechnology, Chonbuk National University, Jeonju, South Korea
  • 6KT&G Central Research Institute, Taejon, South Korea
  • 7Division of Life Science, College of Natural Science, Wonkwang University, Iksan, South Korea
Further Information

Publication History

Received: September 6, 2004

Accepted: January 5, 2005

Publication Date:
21 June 2005 (online)

Abstract

The chemical components of the essential oil obtained from Artemisia lavandulaefolia DC. were analyzed by GC-MS. Ninety-nine compounds accounting for 94.9 % of the essential oil were identified. The major compounds in the essential oil were β-caryophyllene (16.1 %), cis-chrysanthenol (7.0 %), 1,8-cineole (5.6 %), borneol (5.3 %), trans-β-farnesene (5.1 %), camphor (4.9 %), yomogi alcohol (4.5 %), α-terpineol (3.9 %), and α-humulene oxide (3.3 %). The essential oil and some of its major compounds were tested for antimicrobial activity against 15 different genera of oral bacteria. The essential oil of A. lavandulaefolia exhibited considerable inhibitory effects against all obligate anaerobic bacteria (MIC values, 0.025 to 0.05 mg/mL; MBC values, 0.025 to 0.1 mg/mL) tested, while its major compounds demonstrated different degrees of growth inhibition.

References

  • 1 Robles M, Aregullin M, West J, Rodriguez E. Recent studies on the zoopharmacognosy, pharmacology and neurotoxicology of sesquiterpene lactones.  Planta Med. 1995;  61 199-203
  • 2 Park J H. Korean Folk Medicine. Busan; Busan National University Publisher 1999: 68
  • 3 Kil B S, Han D M, Lee C H, Kim Y S, Yun K Y, Yoo H G. Allelopathic effects of A. lavandulaefolia .  Korean J Ecol. 2000;  23 154-5

Prof. Dr. Yo-Han Song

Department of Oral Microbiology

School of Dentistry

664-14 Duckjin-Dong

Duckjin-Ku

Jeonju 561-756

South Korea

Phone: +82-63-270-4023

Fax: +82-63-270-4037

Email: songyh@chonbuk.ac.kr

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