Abstract
Polyfunctional bis-arylzinc reagents are accessible via a new lithium acetylacetonate-catalyzed
iodine-zinc exchange. This protocol tolerates sensitive functional groups (ketones,
aldehydes or isothiocyanates) in the aryl iodides and allows the formation of highly
functionalized zinc reagents. These zinc reagents can be used in a variety of catalyzed
and uncatalyzed transformations.
Key words
functionalized zinc reagents - halogen-metal exchange - cross-coupling - nucleophilic
catalysis
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