Synthesis 2006(5): 839-842  
DOI: 10.1055/s-2006-926328
PAPER
© Georg Thieme Verlag Stuttgart · New York

Copper-Catalyzed N-Arylation of Amines/Amides in Poly(ethylene glycol) as Recyclable Solvent Medium

Srivari Chandrasekhar*, S. Shameem Sultana, Srinivasa Rao Yaragorla, N. Ramakrishna Reddy
Organic division-1, Indian Institute of Chemical Technology, Hyderabad 500 007, India
Fax: +91(40)27160512; e-Mail: [email protected];
Further Information

Publication History

Received 24 August 2005
Publication Date:
07 February 2006 (online)

Abstract

The Buchwald N-arylation of amines and amides is achieved efficiently in PEG (400 Daltons) as solvent medium. The solvent and catalyst recyclability is studied. Interestingly amides underwent N-arylation with better yields.

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