Planta Medica, Table of Contents Planta Med 1998; 64(5): 427-430DOI: 10.1055/s-2006-957474 PapersBiochemistry, Physiology, in vitro Cultures© Georg Thieme Verlag Stuttgart · New YorkVariability of Sesquiterpene Lactones in Neurolaena lobata of Different OriginClaus M. Passreiter1 , Beatriz E. Medinilla Aldana2 1Institut für Pharmazeutische Biologie, Heinrich-Heine-Universität Düsseldorf, Düsseldorf, Germany 2Facultad Ciencias Quimicas y Farmacia, Universidad de San Carlos de Guatemala, Guatemala Ciudad, Guatemala Recommend Article Abstract PDF Download(opens in new window) Buy Article(opens in new window) Abstract Leaves of Neurolaena lobata (L.) R. Br. originating from Guatemala, were analyzed using HPLC for their qualitative and quantitative sesquiterpene lactone contents. Significant differences in the individual amounts of neurolenins and furanoheliangolides were found between four natural populations. When plants were cultivated on proving fields at two different localities in Guatemala, their sesquiterpene lactone patterns matched the natural population, but differed quantitatively. The meaning of these differences for the use of N. lobata in traditional medicine and its cultivation is discussed. Key words Neurolaena lobata - Asteraceae - sesquiterpene lactones - cultivations - natural populations PDF (361 kb)
