New Orthoquinones from the Roots of Salvia lanigera

Ik-Soo Lee; Norito Kaneda; Rutt Suttisri; Abdalla M. El-Lakany; Nawal N. Sabri; A. Douglas Kinghorn

doi:10.1055/s-2006-957536

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Planta Med 1998; 64(7): 632-634
DOI: 10.1055/s-2006-957536

Paper

Natural Product Chemistry
© Georg Thieme Verlag Stuttgart · New York

New Orthoquinones from the Roots of Salvia lanigera

Ik-Soo Lee¹ , Norito Kaneda¹ , Rutt Suttisri¹ , Abdalla M. El-Lakany² , Nawal N. Sabri² , A. Douglas Kinghorn¹

¹Program for Collaborative Research in the Pharmaceutical Sciences and Department of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, University of Illinois at Chicago, Chicago, Illinois, U.S.A.
²Department of Pharmacognosy, Faculty of Pharmacy, University of Alexandria, Alexandria, Egypt

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Publikationsverlauf

1998

1998

Publikationsdatum:
04. Januar 2007 (online)

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Abstract

A chloroform extract of the roots of the Egyptian Salvia lanigera Poir. afforded two new orthoquinones, lanigerone (8-hydroxy-3-isopropyl-7-methyl-1,2-naphthoquinone) and salvigerone (methyl 1,10-seco-5(10),6,8,13-abietatetraene-11,12-dion-1-oate) together with two known diterpenoids, arucadiol and pisiferal. Structural assignments of the new compounds were based on spectroscopic methods (UV, IR, MS, ID- and 2D-NMR).

Key words

Salvia lanigera Poir. - Labiatae - orthoquinones - lanigerone (8-hydroxy-3-isopropyl-7-methyl-1,2-naphthoquinone) - salvigerone (methyl 1,10-seco-5(10),6,8,13-abietatetraene-11,12-dion-1-oate) - arucadiol - pisiferal