Planta Med 1995; 61(3): 267-270
DOI: 10.1055/s-2006-958070

© Georg Thieme Verlag Stuttgart · New York

The Effect of Chelidonium majus Herb Extract on Choleresis in the Isolated Perfused Rat Liver

U. Vahlensieck1 , R. Hahn2 , H. Winterhoff1 , H. G. Gumbinger1 , A. Nahrstedt2 , F. H. Kemper1
  • 1Institut für Pharmakologie und Toxikologie der Westfälischen-Wilhelms Universität, Domagkstr.12, D-48149 Münster, Germany
  • 2Institut für Pharmazeutische Biologie und Phytochemie der Westfülischen-Wilhelms Universitüt, Hittorfstr. 56, D-48149 Münster, Germany
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Publication History



Publication Date:
04 January 2007 (online)


The total ethanolic extract, the phenolic and the alkaloidal fraction of the herb of Chelidonium majus L. (Papaveraceae) were tested for their choleretic activity using the isolated perfused rat liver. The total extract significantly caused chloresis by increasing the bile acid independent flow (BAIF); the observed weak activity of both fractions, tested each and as combination, however, was not significant.