Download PDF
Planta Med 1993; 59(5): 398-400
DOI: 10.1055/s-2006-959717
Paper

© Georg Thieme Verlag Stuttgart · New York

Sedative Effect of Galphimine B, a Nor- seco -triterpenoid from Galphimia glauca

J. Tortoriello1 , A. Ortega2
  • 1Unidad de Investigatiòn Biomédica del Sur, Centre de Investigatiòn de Plantas Medicinales, IMSS, Argentina No. 1, Xochitepec, Morelos, Mexico CP. 62790
  • 2Institute de Química, Universidad Nacional Autonoma de México, México D.F.
Further Information

Publication History

1992

1993

Publication Date:
04 January 2007 (online)

Also available at
  PDF Download  Permissions and Reprints

Abstract

Galphimia glauca Cav. (Malpighiaceae) is used in Mexican traditional medicine as a sedative in the treatment of mental disorders. Sedative properties of a methanolic extract of the aerial parts of this plant have been established in animal trials and an active compound, named galphimine B, has already been isolated. This compound was submitted to neuropharmacological testing, where it was shown that galphimine B had no significant effect as an anticonvulsant, while it exhibited a strong depressant activity on the nervous system.

Key words

Galphimia glauca - Malpighiaceae - nor-seco-triterpenoid - sedative effects - galphimine B.