Planta Medica, Table of Contents Planta Med 1993; 59(5): 398-400DOI: 10.1055/s-2006-959717 Paper © Georg Thieme Verlag Stuttgart · New YorkSedative Effect of Galphimine B, a Nor- seco -triterpenoid from Galphimia glauca J. Tortoriello1 , A. Ortega2 1Unidad de Investigatiòn Biomédica del Sur, Centre de Investigatiòn de Plantas Medicinales, IMSS, Argentina No. 1, Xochitepec, Morelos, Mexico CP. 62790 2Institute de Química, Universidad Nacional Autonoma de México, México D.F. Recommend Article Abstract PDF Download Buy Article Abstract Galphimia glauca Cav. (Malpighiaceae) is used in Mexican traditional medicine as a sedative in the treatment of mental disorders. Sedative properties of a methanolic extract of the aerial parts of this plant have been established in animal trials and an active compound, named galphimine B, has already been isolated. This compound was submitted to neuropharmacological testing, where it was shown that galphimine B had no significant effect as an anticonvulsant, while it exhibited a strong depressant activity on the nervous system. Key words Galphimia glauca - Malpighiaceae - nor-seco-triterpenoid - sedative effects - galphimine B. PDF (189 kb)
