Antiplatelet Components in Panex ginseng

Sheng-Chu Kuo; Che-Ming Teng; Jang-Chang Lee; Feng-Nien Ko; Sheng-Chih Chen; Tian-Shung Wu

doi:10.1055/s-2006-960916

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Planta Med 1990; 56(2): 164-167
DOI: 10.1055/s-2006-960916

Papers

Antiplatelet Components in Panex ginseng

Sheng-Chu Kuo¹ , Che-Ming Teng² , Jang-Chang Lee¹ , Feng-Nien Ko² , Sheng-Chih Chen¹ , Tian-Shung Wu³

¹Graduate Institute of Pharmaceutical Chemistry, China Medical College, 91 Hsueh Shih Road, Taichung, Taiwan, Republic of China
²Pharmacological Institute, College of Medicine, National Taiwan University, Taipei, Taiwan, Republic of China
³Department of Chemistry, National Cheng Kung University, Tainan, Taiwan, Republic of China

Further Information

Publication History

1988

Publication Date:
05 January 2007 (online)

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Abstract

Panaxynol and ginsenosides Ro, Rg₁, and Rg₂ were found to be the main antiplatelet components in the diethyl ether and 1-butanol fractions, respectively, during the activity-guided fractionation of Panax ginseng, Panaxynol inhibited the aggregation, release reaction, and thromboxane formation in rabbit platelets while ginsenosides Ro, Rg₁ and Rg₂ suppressed the release reaction only.

Key words

Panaxynol - ginsenosides - antiplatelet activity - aggregation activity - ATP release - thromboxane formation

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