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Planta Med 1988; 54(4): 305-307
DOI: 10.1055/s-2006-962440
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© Georg Thieme Verlag Stuttgart · New York

Antitumor Constituents from Bulbs of Crocosmia crocosmiiflora

Norio Nagamoto1 , Hideto Noguchi1 , Akira Itokawa1 , Katsuhisa Nakata1 , Kensuke Namba1 , Haruki Nishimura1 , [4] , Matao Matsui2 , Mizuo Mizuno3
  • 1Research Laboratories, Dainippon Pharmaceutical Co., Ltd., 33-94 Enoki-cho, Suita, Osaka 564, Japan.
  • 2Daiichi College of Pharmaceutical Sciences, 22-1 Tamagawa-cho, Minami-ku, Hukuoka 815, Japan.
  • 3Gifu Pharmaceutical University, 6-1 Mitahorahigashi 5-chome, Gifu 502, Japan.
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1987

Publikationsdatum:
24. Januar 2007 (online)

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Abstract

The water extract from the bulbs of Crocosmia crocosmiiflora (Nicholson) N. E. Br. (Iridaceae) and its pass-through fraction obtained by gel-filtration chromtography showed strong antitumor activity against Ehrlich carcinoma ascites and solid in Jcl-ICR mice when administered intraperitoneally. Some chemical studies revealed that the active principles in this plant were saponins consisting of medicagenic acid and polygalacic acid as the major sapogenins, and glucose, xylose, arabinose, rhamnose, and fucose as the sugar moieties.

4 Deceased.