A Short Synthesis of (S)-Pyrrolam A via Domino Oxidation-Wittig Reaction

Abstract

A short synthesis of (S)-pyrrolam A starting from readily available N-(benzyloxycarbonyl)-l-prolinol is described that makes use of a domino primary alcohol oxidation-Wittig reaction as the key step.

Keywords

domino reaction - oxidation - Wittig reaction - asymmetric synthesis - bicyclic compounds

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