Planta Med 1986; 52(2): 105-107
DOI: 10.1055/s-2007-969091
Full Papers

© Georg Thieme Verlag Stuttgart · New York

Plants as Sources of Antimalarial Drugs. Part 31 Eurycoma longifolia

Kit L. Chan3 , Melanie J. O'Neill2 , J. David Phillipson2 , David C. Warhurst4
  • 2Department of Pharmacognosy, The School of Pharmacy, University of London, 29-39 Brunswick Square, London WC1N 1AX
  • 3The School of Pharmaceutical Sciences, University of Sains Malaysia, Minden, Penang, Malaysia
  • 4Department of Medical Protozoology, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1
1 For parts 1 and 2 see references (5) and (6).
Further Information

Publication History


Publication Date:
26 February 2007 (online)


Extracts of Eurycoma longifolia Jack (Simaroubaceae) have been tested for antiplasmodial activity against a multi-drug resistant Thailand strain (K-1) of Plasmodium falciparum in vitro. 10-Hydroxycanthin-6-one, eurycomalactone, eurycomanone and eurycomanol were isolated form the plant. The in vitro antimalarial activities of these compounds are reported together with that of 6-hydroxy-5, 6-dehydroeurycomalactone.