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Planta Med 1986; 52(4): 272-275
DOI: 10.1055/s-2007-969150
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© Georg Thieme Verlag Stuttgart · New York

Pharmacological Actions of Tannic Acid; II. Evaluation of CNS Activity in Animals

Reinaldo N. Takahashi, Thereza C. M. de Lima, Gina S. Morato
  • Departamento de Farmacologia, Universidade Federal de Santa Catarina, 88000 Florianopolis SC, Brazil.
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Publication History

1985

Publication Date:
26 February 2007 (online)

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Abstract

The effects of tannic acid (TA) on some behavioral tests in animals were investigated. A non-specific depressant action of TA was the most salient finding in the present study since TA reduced locomotor activity, potentiated pentobarbital-induced sleeping-time and induced analgesia in mice. No changes were found on the convulsive threshold test in rats. It is concluded that the reported central depressant effects of some crude extracts from plant material could be due to the presence of tannin-like constituents in the plant.