Planta Med 1986; 52(4): 311-314
DOI: 10.1055/s-2007-969162
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© Georg Thieme Verlag Stuttgart · New York

Structural Characterization of Anti-Complementary Polysaccharides from the Leaves of Artemisia princeps

Haruki Yamada1 , Yasuo Otsuka1 , Satoshi Ōmura2
  • 1Oriental Medicine Research Center of the Kitasato Institute, 5-9-1, Shirokane, Minato-ku, Tokyo 108, Japan.
  • 2The Kitasato Institute, 5-9-1, Shirokane, Minato-ku, Tokyo 108, Japan
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Publication History

1986

Publication Date:
26 February 2007 (online)

Abstract

Structural characterizations of the anti-complementary acidic heteroglycans, AAF IIb-2 and IIb-3, obtained from the leaves of Artemisia princeps PAMP have been studied. AAF IIb-2 consists of rhamnose, xylose, arabinose, galactose, glucose and uronic acids (glucuronic acid and galacturonic acid) in the molar ratio of 7.6:7.6:13.0:10.9:3.0:57.9, and AAF IIb-3 consists of the same sugars in the ratio of 3.9:2.6:24.7:19.7:2.6:46.5. Methylation analysis including carboxyl-reduction and also selective enzymolysis using exo-α-L-arabinofuranosidase suggested that AAF IIb-3 has a main chain consisting of (1→4)-linked galacturonic acid and (1→2)-linked rhamnose mostly substituted at the O-4 position. AAF IIb-3 also contained arabino-3,6-galactan moiety and most of the arabinose was present as an α-L-furanosyl residue in the non-reducing terminals and highly branched side chains which mostly attached to the O-3 position of (1→6)-linked galactopyranosyl residue. The basic structure of AAF IIb-2 is similar to that of AAF IIb-3, but IIb-3 has a higher arabinogalactan content than IIb-2.