Planta Med 1985; 51(1): 52-56
DOI: 10.1055/s-2007-969392
Research Articles

© Georg Thieme Verlag Stuttgart · New York

Antiinflammatory Compounds from Plagiorhegma dubium Cell Culture1

Hans Arens, Hartmut Fischer, Sigurd Leyck, Axel Römer, Bernhard Ulbrich
  • A. Nattermann & Cie. GmbH, P.O. Box 350120, D-5000 Cologne 30
1 Part 2 in the series “Novel Compounds from Plant Cell Cultures”
Further Information

Publication History

1984

1984

Publication Date:
26 February 2007 (online)

Abstract

Successive fractionation of a crude methanolic extract of cultured Plagiorhegma dubium cells, followed by assay of the biological activity using cobra venom factor induced paw oedema, led to the detection and isolation of three compounds with antiinflammatory activity. The substances were identified as the protoberberine alkaloid jatrorrhizine and the lignaneglucosides dehydrodiconiferyl-alcohol-4-β-D-glucoside and its isomer dehydrodiconiferyl-alcohol-γ-β-D-glucoside, the latter a compound not previously described in the literature.

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