An Efficient Entry to Amino-Substituted Resorcylic Acid Derivatives for the Synthesis of Platensimycin and Analogues

Philipp Heretsch; Athanassios Giannis

doi:10.1055/s-2007-983843

SHORTPAPER

An Efficient Entry to Amino-Substituted Resorcylic Acid Derivatives for the Synthesis of Platensimycin and Analogues

Philipp Heretsch, Athanassios Giannis*
Institut für Organische Chemie, Universität Leipzig, Johannisallee 29, 04103 Leipzig, Germany
Fax: +49(0341)9736599; e-Mail: giannis@uni-leipzig.de;

Abstract

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Abstract

An efficient entry to protected amino-substituted resorcylic acid derivatives, methyl 3- or 5-amino-2,4-bis(methoxymethoxy)benzoate, is reported. Both derivatives can be used for the synthesis of platensimycin and its analogues.

Key words

amino-resorcylic acid - antibiotic - arene - natural products - platensimycin

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References

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