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TRISPHAT-N Anion Provides Bench-Stable Ruthenium Catalyst
S. Constant, S. Tortoioli, J. Müller, D. Linder, F. Buron, J. Lacour*
University of Geneva, Switzerland
21 February 2008 (online)
Asymmetric ruthenium catalysis is useful for the preparation of chiral allylic compounds through nucleophilic attack at the more substituted position of an allyl-ruthenium fragment. However, these reactions require large amounts (10 mol%) of Cp*Ru type catalysts which are difficult to recover owing to their sensitivity to oxygen and moisture. The present study reports that air- and moisture-stable Cp*Ru complexes are achievable through the use of the anionic monodentate ligand TRISPHAT-N.