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Synthesis 2008(13): 1997-1999
DOI: 10.1055/s-2008-1067106
DOI: 10.1055/s-2008-1067106
SHORTPAPER
© Georg Thieme Verlag Stuttgart · New York
Convenient Conversion of Aldoximes into Nitriles with N-Chlorosuccinimide and Pyridine
Further Information
Received
27 February 2008
Publication Date:
21 May 2008 (online)
Publication History
Publication Date:
21 May 2008 (online)
Abstract
Benzaldehyde oximes substituted with electron-donating groups are dehydrated to the corresponding benzonitriles by N-chlorosuccinimide/pyridine in acetonitrile. Benzaldehyde oxime itself and alkanal oximes afford the corresponding aldehydes.
Key words
aldoxime - aryl nitrile - N-chlorosuccinimide - pyridine - dehydration
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