Solvent- and Metal-Controlled Regiodivergent Synthesis of Tri­fluoromethylated Pyrazol-3-yl- and Pyrazol-5-ylphosphonates

Abstract

Convenient approaches to the selective syntheses of trifluoro­methylated pyrazol-3-yl- and pyrazol-5-ylphosphonates have been developed based on solvent- and metal-controlled reaction of diethyl (4,4,4-trifluoro-3-oxobut-1-yn-1-yl)phosphonate and monosubstituted hydrazines.

Key words

pyrazoles - phosphonates - cyclization - conjugated ynones - organofluorine compounds

• References

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