One-Pot Synthesis of 1,2,3-Triazole-Fused Polycyclic Systems via Sequential Annulation of 1,n-Enynes with Tosyl Azide

Abstract

An efficient one-pot sequential annulation of 1,n-enynes with tosyl azide is reported, providing a series of novel N-alkyl 1,2,3-triazole-fused polycyclic scaffolds in moderate to excellent yields under mild reaction conditions.

Key words

1,n-enyne - tosyl azide - fused 1,2,3-triazole - one-pot reaction - cyclization

Publication History

Received: 13 June 2022

Accepted after revision: 05 July 2022

Accepted Manuscript online:
05 July 2022

Article published online:
09 August 2022

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