Zusammenfassung
Blepharitis ist eine häufige entzündliche Erkrankung der Augenlider
einschließlich des Lidrandes, die bei Erwachsenen und Kindern auftreten und
schwere Symptome hervorrufen haben kann. Je nach anatomischer Lokalisation kann
die Blepharitis in anteriore und posteriore Formen eingeteilt werden. Die
Pathogenese der chronischen Blepharitis ist noch nicht vollständig geklärt, es
wird jedoch ein multifaktorielles Krankheitsgeschehen vermutet. Die Erkrankung
stellt eine therapeutische Herausforderung dar.
Abstract
Blepharitis represents a frequent inflammatory condition of the lids including
the lid margin, which can be apparent in adults and children. Chronic
blepharitis is therapeutically challenging. According to the anatomic
localization, blepharitis can be graded in anterior and posterior forms.
Blepharitis can lead to severe symptoms and complications, mainly dry eye
disease, corneal complications and defective lid position. The pathogenesis of
chronic blepharitis is not fully understood so far, however, multifactorial
disease proceedings are supposed, which include systemic diseases (mainly
dermatological disorders), habitual bacteria and infections. In all these
processes inflammatory changes are the common final path.
Therapeutic strategies include topical and systemic therapies, however evidence
levels are generally low and patients are often resistant to therapy. Basic
therapeutic measures are warm compresses, lid hygiene and lubricants. Topical
anti-inflammatory drugs comprise corticosteroids and ciclosporin A. Topical and
systemic antibiotics are commonly used. Systemic intake of omega-3 fatty acids
is often recommended due to its anti-inflammatory potential.
Schlüsselwörter
Blepharitis - Rosazea - anteriore Blepharitis - posteriore Blepharitis - Meibom-Drüsen-Dysfunktion
Key words
blepharitis - rosacea - anterior blepharitis - posterior blepharitis - meibomian gland dysfunction
