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DOI: 10.1055/a-2486-8994
Impact of Social Determinants of Health on Follow-up for Neonates Requiring Neurocritical Care
Funding This study was supported by a Morris Green Physician Scientist Development Program grant from the Indiana University School of Medicine.The content of the manuscript is solely the responsibility of the authors and does not necessarily represent the official views of the Morris Green Physician Scientist Development Program at Indiana University.

Abstract
Objective
This study aimed exploration of associations of social determinants of health (SDH) with attrition rates of neurocritical care graduates at follow-up.
Study Design
An observational retrospective cohort study was conducted to evaluate the attrition rates of an infant's first appointment scheduled with the NeuroNICU follow-up clinic in correlation with SDH.
Results
The “No Show” group was more likely to have unemployed (p = 0.014), black or multiracial mothers (p = 0.005), public insurance (p < 0.001), lower gestational age (p < 0.001), live further from the clinic (0.011), and a lower zip code-associated income (p = 0.008). After controlling for driving time, race, and education, infants who had private insurance were 2.268 times more likely to attend their follow-up visit when compared with infants who had public insurance (p = 0.014).
Conclusion
A significant SDH-related difference existed among the “Show” and “No Show” groups. Identifying these factors during neonatal intensive care unit (NICU) admission can facilitate targeted support for families while inpatient and promote improved outpatient follow-up.
Key Points
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Follow-up for neonates requiring neurocritical care is strongly influenced by social determinants.
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Standardized SDH screening in NICUs, identifying high-risk infants for attrition, is used by few.
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Factors influencing disparities in the utilization of follow-up programs require further study.
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Equity-based attrition prevention interventions could improve outcomes and reduce costs.
Ethical Approval
This was a research-expedited study approved by the Indiana University Institutional Review Board. The study was performed in accordance with the Declaration of Helsinki.
Publication History
Received: 30 July 2024
Accepted: 25 November 2024
Accepted Manuscript online:
26 November 2024
Article published online:
24 December 2024
© 2024. Thieme. All rights reserved.
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References
- 1 Burke S. Systematic review of developmental care interventions in the neonatal intensive care unit since 2006. J Child Health Care 2018; 22 (02) 269-286
- 2 Séassau A, Munos P, Gire C, Tosello B, Carchon I. Neonatal care unit interventions on preterm development. Children (Basel) 2023; 10 (06) 999
- 3 Smith VC, Love K, Goyer E. NICU discharge preparation and transition planning: guidelines and recommendations. J Perinatol 2022; 42 (Suppl. 01) 7-21
- 4 Swearingen C, Simpson P, Cabacungan E, Cohen S. Social disparities negatively impact neonatal follow-up clinic attendance of premature infants discharged from the neonatal intensive care unit. J Perinatol 2020; 40 (05) 790-797
- 5 Brachio SS, Farkouh-Karoleski C, Abreu A, Zygmunt A, Purugganan O, Garey D. Improving neonatal follow-up: a quality improvement study analyzing in-hospital interventions and long-term show rates. Pediatr Qual Saf 2020; 5 (06) e363
- 6 Bernbaum JC. Chapter 114: Follow-up care of the graduate from neonatal intensive care. In: Textbook of Pediatric Care. 2nd ed.. American Academy of Pediatrics; 2016
- 7 Mas C, Gérardin P, Chirpaz E. et al. Follow-up at two years of age and early predictors of non-compliance in a cohort of very preterm infants. Early Hum Dev 2017; 108: 1-7
- 8 Commission on Social Determinants of Health. Closing the Gap in a Generation: Health Equity Through Action on the Social Determinants of Health. World Health Organization; 2008. . ISBN 978-92-4-156370-3
- 9 Lorch SA, Enlow E. The role of social determinants in explaining racial/ethnic disparities in perinatal outcomes. Pediatr Res 2016; 79 (1-2): 141-147
- 10 Johnson YR, Guillory C, Imaizumi S. Health care disparities in high-risk neonates. Clin Perinatol 2023; 50 (01) 67-80
- 11 Purnell TS, Fakunle DO, Bone LR. et al. Overcoming barriers to sustaining health equity interventions: insights from the National Institutes of Health Centers for Population Health and Health Disparities. J Health Care Poor Underserved 2019; 30 (03) 1212-1236
- 12 Cordova-Ramos EG, Jain C, Torrice V. et al. Implementing social risk screening and referral to resources in the NICU. Pediatrics 2023; 151 (04) e2022058975
- 13 Vandenbroucke JP, von Elm E, Altman DG. et al; STROBE Initiative. Strengthening the reporting of observational studies in epidemiology (STROBE): explanation and elaboration. PLoS Med 2007; 4 (10) e297
- 14 Tang BG, Lee HC, Gray EE, Gould JB, Hintz SR. Programmatic and administrative barriers to high-risk infant follow-up care. Am J Perinatol 2018; 35 (10) 940-945
- 15 Watson L, Woods CW, Cutler A, DiPalazzo J, Craig AK. Telemedicine improves rate of successful first visit to NICU follow-up clinic. Hosp Pediatr 2023; 13 (01) 3-8
- 16 Christner LP, Irani S, McGowan C, Dabaja E, Dejong C, Attar MA. Previous missed visits and independent risk of loss to follow-up in the high-risk neonatal follow-up clinic. Early Hum Dev 2023; 183: 105813
- 17 Harmon SL, Conaway M, Sinkin RA, Blackman JA. Factors associated with neonatal intensive care follow-up appointment compliance. Clin Pediatr (Phila) 2013; 52 (05) 389-396
- 18 Ballantyne M, Stevens B, Guttmann A, Willan AR, Rosenbaum P. Maternal and infant predictors of attendance at neonatal follow-up programmes. Child Care Health Dev 2014; 40 (02) 250-258
- 19 Tin W, Fritz S, Wariyar U, Hey E. Outcome of very preterm birth: children reviewed with ease at 2 years differ from those followed up with difficulty. Arch Dis Child Fetal Neonatal Ed 1998; 79 (02) F83-F87
- 20 Litt JS, Glymour MM, Hauser-Cram P, Hehir T, McCormick MC. Early intervention services improve school-age functional outcome among neonatal intensive care unit graduates. Acad Pediatr 2018; 18 (04) 468-474
- 21 McGowan EC, Vohr BR. Neurodevelopmental follow-up of preterm infants: What is new?. Pediatr Clin North Am 2019; 66 (02) 509-523
- 22 Spittle AJ, Anderson PJ, Tapawan SJ, Doyle LW, Cheong JLY. Early developmental screening and intervention for high-risk neonates - from research to clinical benefits. Semin Fetal Neonatal Med 2021; 26 (03) 101203
- 23 Davis BE, Leppert MO, German K, Lehmann CU, Adams-Chapman I. Council on Children with Disabilities, Committee on Fetus and Newborn. Primary care framework to monitor preterm infants for neurodevelopmental outcomes in early childhood. Pediatrics 2023; 152 (01) e2023062511
- 24 Page BF, Hinton L, Harrop E, Vincent C. The challenges of caring for children who require complex medical care at home: ‘The go between for everyone is the parent and as the parent that's an awful lot of responsibility’. Health Expect 2020; 23 (05) 1144-1154
- 25 Orton JL, Olsen JE, Ong K, Lester R, Spittle AJ. NICU graduates: the role of the allied health team in follow-up. Pediatr Ann 2018; 47 (04) e165-e171
- 26 United States Census Bureau. Accessed December 3, 2024 at: https://www.census.gov/quickfacts/fact/table/IN/PST0452220
- 27 Gibson-Davis C, Keister LA, Gennetian LA, Lowell W. Net worth poverty and child development. Socius 2022; (e-pub ahead of print)
- 28 DeGuzman P, Altrui P, Doede AL, Allen M, Deagle C, Keim-Malpass J. Using geospacial analysis to determine access gaps among children with special healthcare needs. Health Equity 2018; 2 (01) 1-4
- 29 Loccoh EC, Nguyen A, Kim G, Warraich HJ. Geospacial analysis of access to health care and internet services in the US. JAMA Network 2022; 5 (11) 1-4
- 30 Trent M, Dooley DG, Douge J. Section on Adolescent Health, Council on Community Pediatrics, Committee on Adolescence. The impact of racism on child and adolescent health. In: Adolescent Health. American Academy of Pediatrics; 2020: 331-344
- 31 Ray KN, Kahn JM. Connected subspecialty care: applying telehealth strategies to specific referral barriers. Acad Pediatr 2020; 20 (01) 16-22
- 32 Nehra V, Pici M, Visintainer P, Kase JS. Indicators of compliance for developmental follow-up of infants discharged from a regional NICU. J Perinat Med 2009; 37 (06) 677-681
- 33 Ballantyne M, Liscumb L, Brandon E, Jaffar J, Macdonald A, Beaune L. Mothers' perceived barriers to and recommendations for health care appointment for children who have cerebral palsy. Glob Qual Nurs Res 2019; 6: 2333393619868979
- 34 Parker MG, Garg A, Brochier A. et al. Approaches to addressing social determinants of health in the NICU: a mixed methods study. J Perinatol 2021; 41 (08) 1983-1991