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DOI: 10.1055/a-2542-9318
Reoperation following Cesarean Birth: An Analysis of Incidence, Indications, and Procedures Using a National Surgical Database
Funding None.
Abstract
Objective
This study aimed to determine the incidence of reoperation after uncomplicated cesarean birth, describe the types of procedures and indications for reoperation, and identify risk factors associated with reoperation using a national surgical database.
Study Design
A retrospective cross-sectional study was conducted using the American College of Surgeons National Surgical Quality Improvement Program database, encompassing data from January 1, 2019, to December 31, 2021. A total of 43,492 patients who underwent cesarean birth were included. Patients who underwent concurrent nongynecologic procedures or hysterectomies were excluded. The primary outcomes measured were the incidence of unplanned reoperation within 30 days of cesarean birth, types of reoperative procedures, indications for reoperation, and associated risk factors. Statistical analyses included Student's t-test, Wilcoxon rank-sum test, chi-squared test, and multivariable logistic regression.
Results
Out of 43,492 cesarean deliveries, 397 (0.9%) required unplanned reoperation. Significant risk factors for reoperation included smoking (adjusted odds ratio [aOR]: 1.96, 95% confidence interval [CI]: 1.49–1.56), hypertension (aOR: 1.83, 95% CI: 1.27–2.62), bleeding disorders (aOR: 2.11, 95% CI: 1.15–3.89), American Society of Anesthesiologists (ASA) class > 3 (aOR: 2.23, 95% CI: 1.29–3.84), and concurrent myomectomy (aOR: 4.39, 95% CI: 1.06–18.2). The most common indications for reoperation were postpartum hemorrhage (47%), wound disruption or infection (18%), and hematoma or hemoperitoneum (14%). The most frequently performed reoperative procedures were exploratory laparotomy without hysterectomy (27%), uterine curettage (23%), and wound debridement or drainage (22%).
Conclusion
Reoperation following cesarean birth is a relatively uncommon but significant event, occurring in 0.9% of cases. Key risk factors include smoking, hypertension, bleeding disorders, ASA class > 3, and concurrent myomectomy. This study provides comprehensive data on the clinical characteristics and indications for reoperation following cesarean birth in a diverse, multi-institutional US cohort. The findings highlight the need for enhanced perioperative monitoring and targeted interventions for high-risk patients to improve maternal outcomes.
Key Points
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In this retrospective cross-sectional study of 43,492 cesarean deliveries, the incidence of unplanned reoperation was found to be 0.9%.
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Significant risk factors for reoperation included smoking, hypertension, bleeding disorders, American Society of Anesthesiologists (ASA) class > 3, and concurrent myomectomy at the time of cesarean birth.
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The most common indications for reoperation were postpartum hemorrhage, wound disruption or infection, and hematoma or hemoperitoneum.
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The most common reoperative procedures were exploratory laparotomy without hysterectomy, uterine curettage, and wound debridement or drainage.
Keywords
cesarean birth - current procedural terminology (CPT) - dilation and curettage - hysterectomy - international classification of diseases (ICD) - laparotomy - NSQIP - postoperative complications - postpartum hemorrhage - reoperation - relaparotomyPublication History
Received: 07 October 2024
Accepted: 19 February 2025
Accepted Manuscript online:
20 February 2025
Article published online:
18 March 2025
© 2025. Thieme. All rights reserved.
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References
- 1 Births: Provisional Data for 2023. Centers for Disease Control and Prevention. Accessed 2024 at: https://www.cdc.gov/nchs/data/vsrr/vsrr035.pdf
- 2 Creanga AA, Bateman BT, Butwick AJ. et al. Morbidity associated with cesarean delivery in the United States: is placenta accreta an increasingly important contributor?. Am J Obstet Gynecol 2015; 213 (03) 384.e1-384.e11
- 3 Mackeen AD, Sullivan MV, Berghella V. Evidence-based cesarean delivery: preoperative management (part 7). Am J Obstet Gynecol MFM 2024; 6 (05) 101362
- 4 Corbetta-Rastelli CM, Friedman AM, Sobhani NC, Arditi B, Goffman D, Wen T. Postpartum hemorrhage trends and outcomes in the United States, 2000-2019. Obstet Gynecol 2023; 141 (01) 152-161
- 5 Hammad IA, Chauhan SP, Magann EF, Abuhamad AZ. Peripartum complications with cesarean delivery: a review of maternal-fetal medicine units network publications. J Matern Fetal Neonatal Med 2014; 27 (05) 463-474
- 6 Carter EB, Temming LA, Fowler S. et al. Evidence-based bundles and cesarean delivery surgical site infections: a systematic review and meta-analysis. Obstet Gynecol 2017; 130 (04) 735-746
- 7 Temming LA, Raghuraman N, Carter EB. et al. Impact of evidence-based interventions on wound complications after cesarean delivery. Am J Obstet Gynecol 2017; 217 (04) 449.e1-449.e9
- 8 Belfort MA, Clark SL, Saade GR. et al. Hospital readmission after delivery: evidence for an increased incidence of nonurogenital infection in the immediate postpartum period. Am J Obstet Gynecol 2010; 202 (01) 35.e1-35.e7
- 9 Batra P, Fridman M, Leng M, Gregory KD. Emergency department care in the postpartum period: California births, 2009-2011. Obstet Gynecol 2017; 130 (05) 1073-1081
- 10 Akkurt MO, Coşkun B, Güçlü T, Çift T, Korkmazer E. Risk factors for relaparotomy after cesarean delivery and related maternal near-miss event due to bleeding. J Matern Fetal Neonatal Med 2020; 33 (10) 1695-1699
- 11 Ashwal E, Yogev Y, Melamed N. et al. Characterizing the need for re-laparotomy during puerperium after cesarean section. Arch Gynecol Obstet 2014; 290 (01) 35-39
- 12 Gedikbasi A, Akyol A, Asar E. et al. Re-laparotomy after cesarean section: operative complications in surgical delivery. Arch Gynecol Obstet 2008; 278 (05) 419-425
- 13 Huras H, Radon-Pokracka M, Nowak M. Relaparotomy following cesarean section - a single center study. Eur J Obstet Gynecol Reprod Biol 2018; 225: 185-188
- 14 Kessous R, Danor D, Weintraub YA. et al. Risk factors for relaparotomy after cesarean section. J Matern Fetal Neonatal Med 2012; 25 (11) 2167-2170
- 15 Levin I, Rapaport AS, Salzer L, Maslovitz S, Lessing JB, Almog B. Risk factors for relaparotomy after cesarean delivery. Int J Gynaecol Obstet 2012; 119 (02) 163-165
- 16 Levitt L, Sapir H, Kabiri D, Ein-Mor E, Hochner-Celnikier D, Amsalem H. Re-laparotomy following cesarean delivery - risk factors and outcomes. J Matern Fetal Neonatal Med 2016; 29 (04) 607-609
- 17 Lurie S, Sadan O, Golan A. Re-laparotomy after cesarean section. Eur J Obstet Gynecol Reprod Biol 2007; 134 (02) 184-187
- 18 Raagab AE, Mesbah YH, Brakat RI, Zayed AA, Alsaammani MA. Re-laparotomy after cesarean section: risk, indications and management options. Med Arh 2014; 68 (01) 41-43
- 19 Seal SL, Kamilya G, Bhattacharyya SK, Mukherji J, Bhattacharyya AR. Relaparotomy after cesarean delivery: experience from an Indian teaching hospital. J Obstet Gynaecol Res 2007; 33 (06) 804-809
- 20 Seffah JD. Re-laparotomy after cesarean section. Int J Gynaecol Obstet 2005; 88 (03) 253-257
- 21 Shinar S, Hareuveni M, Ben-Tal O, Many A. Relaparotomies after cesarean sections: risk factors, indications, and management. J Perinat Med 2013; 41 (05) 567-572
- 22 Vázquez-Rodríguez JG, Serrano-Rodríguez J, Arredondo-Andrade SA, Chable-Chan FG, García-Bello JA, Nájera-Coutiño CM. Prevalencia, causas y curso clínico de pacientes con reintervención quirúrgica debido a complicaciones durante la cesárea. Cir Cir 2023; 91 (04) 446-450
- 23 Amikam U, Botkovsky Y, Hochberg A. et al. Risk factors for relaparotomy after a cesarean delivery: a case-control study. BMC Pregnancy Childbirth 2024; 24 (01) 284
- 24 Pencole L, Peyronnet V, Mandelbrot L, Lepercq J. Risk factors of relaparotomy for intra-abdominal hemorrhage after cesarean delivery. Eur J Obstet Gynecol Reprod Biol 2021; 260: 118-123
- 25 Wen T, Liao L, Kern-Goldberger A. et al. Risk for and temporal trends in cesarean surgical complications. J Matern Fetal Neonatal Med 2022; 35 (25) 6489-6497
- 26 Pergialiotis V, Sinanidis I, Louloudis I-E, Vichos T, Perrea DN, Doumouchtsis SK. Perioperative complications of cesarean delivery myomectomy: a meta-analysis. Obstet Gynecol 2017; 130 (06) 1295-1303
- 27 Mandelbaum RS, Matsuzaki S, Sangara RN. et al. Paradigm shift from tubal ligation to opportunistic salpingectomy at cesarean delivery in the United States. Am J Obstet Gynecol 2021; 225 (04) 399.e1-399.e32
- 28 Roeckner JT, Sawangkum P, Sanchez-Ramos L, Duncan JR. Salpingectomy at the time of cesarean delivery: a systematic review and meta-analysis. Obstet Gynecol 2020; 135 (03) 550-557
- 29 Jaffer D, Singh PM, Aslam A, Cahill AG, Palanisamy A, Monks DT. Preventing postpartum hemorrhage after cesarean delivery: a network meta-analysis of available pharmacologic agents. Am J Obstet Gynecol 2022; 226 (03) 347-365
- 30 Al-Zirqi I, Vangen S, Forsén L, Stray-Pedersen B. Effects of onset of labor and mode of delivery on severe postpartum hemorrhage. Am J Obstet Gynecol 2009; 201 (03) 273.e1-273.e9