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Synfacts 2025; 21(05): 530
DOI: 10.1055/a-2557-9945
Innovative Drug Discovery and Development

Tetrel Bonding between an sp2 Nitrogen Atom and an sp3 C–N σ* Bond Stabilizes a cis-Amide Geometry

Authors

    Contributor(s):

  • Antonia F. Stepan (Roche)

  • Nicholas A. Meanwell (Baruch S. Blumberg Inst., U. Michigan, Rutgers. U.)

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Keywords

conformational bias - tetrel bonding - n→σ* interaction


Publication History

Article published online:
22 April 2025

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