DOI: 10.1055/s-00000131

Synfacts

Issue 05 · Volume 21 · May 2025 DOI: 10.1055/s-015-61575

Synthesis of Natural Products

  • z443

    All PDFs of this category

  • 443

    Total Synthesis of (–)-Rubriflordilactone B

  • 444

    Total Synthesis of (+)-Kobusine

  • 445

    Total Synthesis of (–)-Janthinoid A

  • 446

    Total Synthesis of (+)-Berkeleyacetal D

  • 447

    Total Synthesis of (–)-ent-Caucanolide E and (+)-Caucanolide F

  • 448

    Total Synthesis of (–)-Asperone A

  • 449

    Total Synthesis of (+)-Shahamin K

    • Synthesis of Heterocycles

  • z451

    All PDFs of this category

  • 451

    Selective and Sequential Aryne Generations to Build Multisubstituted Naphthalenes

  • 452

    Rational Catalyst Design for the Asymmetric Ring-Opening of Azetidines

  • 453

    Transition-Metal-Free Selective C2- or C4-Alkylation of Pyridines

  • 454

    Modular Bioisosteric Replacement of Pyridine Cores with Benzonitriles

  • 455

    Three-Step Sequence for the Formal β-C(sp3)–H Fluorination of N-Substituted Amines

  • 456

    A One-Pot Three-Component Synthesis of 2,4-Substituted Quinazolines

  • 457

    Aerobic Oxidative Cyclization of N-Containing Heterocycles by Perylene Diimide Catalysis

  • 458

    Construction of 5-Substituted Oxazoles from Aryl Methyl Ketones Using PIDA

  • 459

    Employing Manganese in Cascade Cyclization of Tertiary Enamides into 1,2-Dihydropyridines and Pyridines

    • Synthesis of Materials and Unnatural Products

  • z461

    All PDFs of this category

  • 461

    Ligand-Stabilized Triplet Nitrenes

  • 462

    Silyllithium-Promoted Ring Expansion of Bicyclobutanes

  • 463

    From Boroles to Borirenes

  • 464

    π-Extended Indoloindolizine: A New Semiconducting Module

  • 465

    A [2,2]Pyrenophane from Photodesulfurization

  • 466

    Azuacenes: Azulene-Fused Acenes

  • 467

    Imine-to-Olefin Switching in Single-Crystal Covalent Organic Frameworks

  • 468

    Creating Spirocenters in Polymerization

  • 469

    Dithioacetal Polymers from Photopolycondensation

  • 470

    Ring Expansion Metathesis Polymerization of Polar Monomers

  • 471

    Decarboxylative Ring-Opening Polymerization of N-Carboxyanhydrides

    • Metals in Synthesis

  • z473

    All PDFs of this category

  • 473

    Synthesis of Bicyclic Piperidines Enabled by a Palladium(IV) Dyotropic Rearrangement

  • 474

    Visible-Light-Driven Gold-Catalyzed Cross-Coupling of Aryl Bromides with Carboxylic Acids

  • 475

    Regiodivergent Synthesis of Cyclohexenes and Cyclobutenes under Palladium Catalysis

  • 476

    Iron-Catalyzed Alkenylzincation of Terminal Allenes with Abnormal Regioselectivity

  • 477

    Enantioselective Aziridination of Methyleneoxindoles Enabled by Nickel Catalysis

  • 478

    Catalytic Deoxygenative Arylation of Amides with Aryl Iodides to Access β-Aryl Amines

  • 479

    One-Pot Diazotization and Asymmetric Heck Reaction between Anilines and Unactivated Alkenes

  • 480

    Iridium-Catalyzed Enantioselective Partial Hydrogenation of Quinolines to 1,4-Dihydroquinolines

  • 481

    Synthesis of Five- and Six-Membered Rings from Dienes Catalyzed by Nickel

  • 482

    Asymmetric C(sp3)–H Functionalization of Allylic Ethers under Dual Nickel and Photoredox Catalysis

  • 483

    A Rhodium- and NHC-Catalyzed One-Pot Sequence for the Synthesis of Pyrrole-Fused Lactones

  • 484

    Synthesis of Isocyanates by Light-Driven Nickel-Catalyzed Carbonylative Azidation of Alkyl Iodides

  • 485

    Directed Silylalkenylation of ortho-C–H Bonds Catalyzed by Rhenium

  • 486

    Palladium-Catalyzed Skeletal Rearrangement of Small-Ring Carboxylic Acids to α,β-Unsaturated δ/γ-Lactones

  • 487

    [8+1] Cycloaddition of Vinyl Biscyclopropanes with CO Catalyzed by Rhodium

  • 488

    Copper-Catalyzed Asymmetric Epoxidation of Aldehydes with α-Trifluoromethyl Diazosilanes

  • 489

    Photochemical Palladium-Catalyzed Functionalization of 4-Acetoxy Piperidines via 1,5-Hydrogen Atom Transfer

  • 490

    Nickel-Catalyzed Regiodivergent Hydrocyanation of Alkynes

  • 491

    Asymmetric Synthesis of Spirocycles via Nickel-Catalyzed Alkenylation of Bisnucleophiles

  • 492

    Copper-Catalyzed anti-Selective Silylarylation of Benzylacetylenes

  • 493

    Trifluoromethyl Thiosulfonylation of Aryl Silicon Nucleophiles under Bismuth Catalysis

  • 494

    Regio- and Stereoselective Desymmetrization of Alkyne-Tethered Cyclic 1,3-Diones to Access Hydrobenzofurans

  • 495

    Combination of Rh-Hydrogen-Borrowing Catalysis and Pd-Catalyzed α-Arylation to Access α-Aryl Amines

  • 496

    Palladium-Catalyzed Asymmetric Heck/Tsuji–Trost Allylic Alkoxylation of Cyclohexadiene Derivatives

  • 497

    Synthesis of Chiral Allylic Sulfones via Regio- and Enantioselective Protoboration of Allenyl Sulfones

  • 498

    Accessing Cyclopentenones via Intramolecular Rhodium-Catalyzed Hydroacylation of Alkynyl Aldehydes

    • Polymer-Supported Synthesis

  • z499

    All PDFs of this category

  • 499

    Photocatalytic Aerobic Oxidation of Amines Using Poly(phenylene ethynylene)

  • 500

    Nickel-Catalyzed Aryl-Carbonylative Ring-Opening of Oxiranes/Oxetanes under Electroreductive Conditions

  • 501

    Direct Dehydrative Esterification Using a Chitosan-Supported Ionic Liquid Catalyst

  • 502

    Aerobic Oxidation of Alcohols and Sulfides Using a Terbium MOF Catalyst under Photoirradiation

  • 503

    Diazenylation of Cyclic 1,3-Dicarbonyl Compounds with Aryldiazonium Tetrafluoroborates Using a TiO2 Catalyst

  • 504

    β-Selective Functionalization of Styrenes Using a Triazine-Based COF Photocatalyst

  • 505

    Difluoromethylation/Cyclization of 2-Isocyanobiaryls with an N-Phenylphenothiazine-Based Polymer Catalyst

  • 506

    Selective Hydrogenation of Nitroarenes with a Graphene-Supported Co/Mn Bimetallic Catalyst

  • 507

    Borylation of C(sp3)–O Bonds of Alkyl Ethers by Using Gold Nanoparticles Supported on α-Fe2O3

  • 508

    Hydrogenative Hydrogenolysis of Aromatic Aldehydes Using Single-Atom Palladium Supported on COF

  • 509

    Formation of Quinoline N-Oxides by Electrochemical Reductive Cyclization of 2-AllylNitroarenes

    • Organo- and Biocatalysis

  • z511

    All PDFs of this category

  • 511

    Synergistic Phase-Transfer Catalysis for Nucleophilic Fluorination

  • 512

    An Acridinium Photocatalyst Enables Anti-Markovnikov Hydration of Unconjugated Olefins

  • 513

    Biomimetic Photodecarboxylation of Amino Acids

  • 514

    Asymmetric Radical Azidation via Bioinspired Copper/Amine Cooperative Catalysis

  • 515

    para-Selective C–H Alkylation via Radical tele-Substitution

  • 516

    Organo-Electro Catalysis for Asymmetric Biaryldiol Synthesis

  • 517

    Haloperoxidases: Vanadium-Dependent Metalloenzymes for Sustainable Halogenation

  • 518

    Controlled Partial and Complete Reductions of Furans Catalyzed by Simple Brønsted Acids

  • 519

    Electrophilic Bromination of Electron-Deficient Arenes

  • 520

    Asymmetric Imine Addition to Azabicyclo[1.1.0]butanes as Precursors to 2-Substituted Bicyclo[1.1.1]pentanes

    • Innovative Drug Discovery and Development

  • z521

    All PDFs of this category

  • 521

    Organocatalyst for Regioselective Lactonization

  • 522

    Regioselective Thiolation of 2,4-Dihalopyrimidines

  • 523

    New Synthesis of Mirogabalin – A Counterintuitive Approach

  • 524

    A Quick Ibogaine Synthesis Amenable to Late-Stage Diversification

  • 525

    Stereodivergent Sequential Catalysis Provides Access to Highly Functionalized Oxindoles

  • 526

    Are You Positive? Establishing Cocaine Protonation upon DAT Binding with pH-Sensitive Anthracene Probe

  • 527

    ‘Cut-and-Sew’ Aryne Insertion into Benzocyclobutenones

  • 528

    Skeletal Editing Approach to Synthesize Fluorinated Oxetane Isosteres

  • 529

    Ruthenium-Catalyzed N-Heterocycle Allylation via C–H Activation

  • 530

    Tetrel Bonding between an sp2 Nitrogen Atom and an sp3 C–N σ* Bond Stabilizes a cis-Amide Geometry

  • 531

    The Development of a Ratiometric Low-Affinity Calcium Indicator

  • 532

    Proteomic Profiling of Rabeprazole’s Cellular Targets and Its Zinc-Mediated Activity

  • 533

    mRNA Display Elicits Cyclic Peptide Covalent Binders of Staphylococcus aureus Serine Hydrolase

    • Peptide Chemistry

  • z535

    All PDFs of this category

  • 535

    Peptide Stapling and Conjugation via Reversible Crosslinking of Two Alkyl Amines Using Formamidine

  • 536

    Cobalt-Catalyzed Reductive Tandem Reaction for the General Synthesis of Functional Amino Acids

  • 537

    Synthesis of Biaryl α-Amino Acids from Tyrosine via One-Pot Palladium-Catalyzed Arylation

  • 538

    Synthesis of Chiral β-Amino Esters from Diazoesters and N‐Methyl Tertiary Amines Using an Iridium Complex

  • 539

    Synthesis of Quinoxalinones Containing Heteroaryl Alanines and Oligopeptides

  • 540

    Synthesis of Cyclohexyl Analogues of Clovibactin

  • 541

    Chemical Synthesis of Stylissamide H

  • 542

    Pd(II)-Catalyzed C(sp2)–H Arylation of Dehydroalanine-Containing Peptides with Arylthianthrenium Salts

  • 543

    Flavin-Catalyzed Deprotection of C-Terminus Arylacyl Esters

  • 544

    Redox-Neutral Photocatalytic Phosphorylation of Tyrosine and Tyrosine-Containing Peptides

  • 545

    C–S Bond Activation of N-Aryl-α-benzylthio Glycine Esters to Access N-Aryl-α-arylated Glycine Esters

  • 546

    Asymmetric Strecker Synthesis for the Synthesis of α-Amino Nitriles

    • Flow Chemistry

  • z547

    All PDFs of this category

  • 547

    Continuous-Flow Synthesis of Cyclopropanes Enabled by Electroreductive Nickel Catalysis